Submit Manuscript  

Article Details

Pleiotropic Effects of ARB in Diabetes Mellitus

[ Vol. 9 , Issue. 2 ]


Shu-ichi Saitoh and Yasuchika Takeishi   Pages 136 - 144 ( 9 )


Evidence accumulated to date indicates that inhibition of the renin-angiotensin system with angiotensin receptor blockers (ARB) may prevent new-onset of diabetes. ARB is also used for the prevention of occurrence and progression of complications in diabetes and diabetic nephropathy. From the results of recent large-scale clinical studies, ARB is considered as a first choice drug in hypertensive patients with diabetes. In this review article, we focus on the effects of ARB on progression and prevention against diabetes as a metabolic-improving agent.


Metabolism, prevention, nephropathy, retinopathy


Department of Cardiology and Hematology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.

Read Full-Text article