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Pleiotropic Effects of ARB in Diabetes Mellitus

[ Vol. 9 , Issue. 2 ]

Author(s):

Shu-ichi Saitoh and Yasuchika Takeishi   Pages 136 - 144 ( 9 )

Abstract:


Evidence accumulated to date indicates that inhibition of the renin-angiotensin system with angiotensin receptor blockers (ARB) may prevent new-onset of diabetes. ARB is also used for the prevention of occurrence and progression of complications in diabetes and diabetic nephropathy. From the results of recent large-scale clinical studies, ARB is considered as a first choice drug in hypertensive patients with diabetes. In this review article, we focus on the effects of ARB on progression and prevention against diabetes as a metabolic-improving agent.

Keywords:

Metabolism, prevention, nephropathy, retinopathy

Affiliation:

Department of Cardiology and Hematology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.



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