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Is Impaired Flow-Mediated Dilatation of the Brachial Artery a Cardiovascular Risk Factor?

[ Vol. 1 , Issue. 2 ]


Stefan Agewall   Pages 107 - 109 ( 3 )


Endothelial dysfunction is thought to be an important factor in the development of atherosclerosis. Over the past decade, a non-invasive technique has evolved to evaluate flow-mediated vasodilation (FMD), an endothelium-dependent function, in the brachial artery. FMD decreases with increasing age and subjects with diabetes mellitus, hypercholesterolemia, smokers and hypertension have decreased FMD. There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation.


flow-mediated dilatation, brachial artery, cardiovascular risk factor?, flow-mediated vasodilation, hypercholesterolemia, coronary artery disease


Department of Cardiology, Huddinge University, Hospital Karolinska Institute, S 141 86, Stockholm,Sweden

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