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Dyslipidaemia, Hypercoagulability and the Metabolic Syndrome

[ Vol. 4 , Issue. 3 ]

Author(s):

Anna I. Kakafika, Evagelos N. Liberopoulos, Asterios Karagiannis, Vasilios G. Athyros and Dimitri P. Mikhailidis   Pages 175 - 183 ( 9 )

Abstract:


The metabolic syndrome is a clustering of risk factors including central obesity, insulin resistance, dyslipidaemia and hypertension. This syndrome is associated with increased risk of cardiovascular disease and is a common early abnormality in the development of type 2 diabetes. The pathogenesis of the syndrome has multiple origins. Obesity and sedentary lifestyle coupled with genetic factors interact to produce the syndrome. Here, we consider two components of the metabolic syndrome, dyslipidaemia and hypercoagulability.

Keywords:

Metabolic syndrome, obesity, insulin resistance, dyslipidaemia, coagulation, ree fatty acids, high density lipoprotein, triglycerides

Affiliation:

Department of Clinical Biochemistry,Royal Free Hospital, Pond Street, London NW3 2QG, UK.



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