Submit Manuscript  

Article Details


Stem-Cell Derived Exosomes for the Treatment of Osteoarthritis

[ Vol. 15 , Issue. 7 ]

Author(s):

Zekai Ke and Jinyu Zhu*   Pages 597 - 601 ( 5 )

Abstract:


Osteoarthritis(OA) is a common degenerative orthopedic disease with multiple pathologic changes in joints affecting large populations worldwide. No treatment can reverse the progress of OA. Since exosomes were first reported in 1983, researches have been conducted to explore the mechanisms and therapeutic potential of exosomes in treating OA. Exosomes derived from Mesenchymal stem cells have attracted increasing attention in tackling the disease. This article summarizes the current advances and challenges in exosomes for OA, which may providea reference for further research.

Keywords:

MSC exosomes, exosomes, osteoarthritis, micro-RNA, cytokines, microenvironment.

Affiliation:

Department of Orthopaedics, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen, Guangdong Province 518055, Department of Orthopaedics, Shenzhen University General Hospital, Shenzhen University Clinical Medical Academy, Shenzhen, Guangdong Province 518055



Read Full-Text article