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The Bleeding Risk in Antithrombotic Therapies: A Narrative Review

[ Vol. 18 , Issue. 3 ]

Author(s):

Adriano Alatri and Lucia Mazzolai*   Pages 237 - 248 ( 12 )

Abstract:


Bleeding represents the most important complication of antithrombotic treatment, including anticoagulant and antiplatelet therapies. A number of scores were proposed to evaluate the risk of bleeding both for anticoagulant and antiplatelet treatment. In the last decade, 5 bleeding risk scores were published for use in atrial fibrillation patients, and 3 scores for patients receiving anticoagulants for venous thromboembolism therapy or prophylaxis. In addition, 3 scores were recently developed to assess inhospital or short-term bleeding risk in patients receiving antiplatelet therapy after Acute Coronary Syndrome (ACS) and Percutaneous Coronary Intervention (PCI). Furthermore, 3 additional scores have focused on long-term bleeding in outpatients receiving dual antiplatelet therapy after PCI. The aim of this review is to consider the evidence on bleeding scores.

Keywords:

Bleeding, clinical predictive rules, atrial fibrillation, venous thromboembolism, acute coronary syndrome, percutaneous coronary intervention, anticoagulants, antiplatelet therapy.

Affiliation:

Division of Angiology, Heart and Vessel Department, Lausanne University Hospital, Lausanne, Division of Angiology, Heart and Vessel Department, Lausanne University Hospital, Lausanne

Graphical Abstract:



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