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Dietary Regulation of Glucose Metabolism in Metabolic Syndrome

[ Vol. 11 , Issue. 6 ]


Monica Bullo, Patricia Cozar-Torrell and Jordi Salas-Salvado   Pages 928 - 945 ( 18 )


Diet and lifestyle are major modifiable determinants of inflammation, hypertension, atherogenic dyslipidemia, glucose metabolism and central obesity and should be targeted for the prevention and treatment of the metabolic syndrome. As insulin resistance, raised fasting and postprandial insulin levels, impaired carbohydrate tolerance and, ultimately, diabetes (all components of the metabolic syndrome) have been related to increased cardiovascular risk, in this report we review the potential role that individual nutrients, foods/food groups, and dietary patterns play in insulin sensitivity and secretion in the management of metabolic syndrome. We also discuss the effect of diet alone on inflammation and the homeostatic control of glucose, regardless of the effect of exercise and weight loss.


Diabetes, diet, dietary pattern, glucose metabolism, inflammation, insulin resistance, metabolic syndrome.


Human Nutrition Unit, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, C/Sant Llorenc¸ 21, 43201 Reus, Spain.

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